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Systasy

Systasy aims to deliver unmatched mode-of-action insight through highly multiplexed phenogenomic pathway profiling technologies for target selection, lead discovery and safety profiling. Its flagship technology, EXTassay, provides simultaneous analysis of multiple cellular and signalling events by utilizing molecularly barcoded reporters. The unmatched depth offered by this technology allows clients to decode target specificity and cellular effector profiles within one experiment.

In addition, Systasy’s proprietary splitSENSOR technology monitors and quantitatively measures cellular events such as regulated protein-protein interactions at the membrane and cytosol levels. Another unique value proposition of Systasy are extensive capabilities around human iPSC-based disease models. Combining the strength of these technologies allows to directly examine what´s going wrong in cells of patients suffering from complex diseases like brain disorders. Furthermore, their aptitude to provide integrated data on cell signalling through extensive parallel phenogenomic profiling technologies, thereby increasing in-depth mode-of-action knowledge are distinguished.

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Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. This work was also partly supported by the Swiss State Secretariat for Education, Research, and Innovation (SERI) under contract No. 22.00115.